This medication is used in certain people to treat outbreaks of herpes simplex infection of the skin (e.g., genitals), mucous membrane areas (e.g., mouth, nose), or brain. It is also used in certain people to treat shingles infection. The viruses that cause these infections live in the body quietly until an outbreak occurs. Acyclovir does not cure these infections, but can speed healing of the sores, decrease pain/itching/formation of new sores, and lower the risk of other problems from the virus (e.g., infection spreading to other parts of the body/organs, persistent pain after sores heal).
This medication is given by slow injection into a vein as directed by your doctor. It is usually given every 8 hours. It should be injected slowly over 1 hour. Do not inject rapidly. Start this medication as soon as signs or symptoms of a herpes infection occur. Dosage is based on your medical condition, weight, and response to treatment.
If you are giving this medication to yourself at home, learn all preparation and usage instruction from your health care professional. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely.
This medication works best when the amount of medicine in your body is kept at a constant level. Therefore, use this drug at evenly spaced intervals.
Continue to use this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may result in a return of the outbreak.
Drink plenty of fluids while receiving this medication unless your doctor directs you otherwise.
Tell your doctor if your condition persists or worsens.
Tell your doctor right away if you have any serious side effects, including: pain/swelling at the injection site, shaking, dizziness, drowsiness, unusual tiredness, fast/pounding heartbeat, easy bruising/bleeding, new signs of infection (e.g., fever, persistent sore throat), bloody/dark urine, severe stomach/abdominal pain, yellowing eyes/skin, change in the amount of urine, mental/mood changes (e.g., agitation, confusion, hallucinations), loss of consciousness, vision changes, seizures.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
In the US -
Before using acyclovir, tell your doctor or pharmacist if you are allergic to it; or to valacyclovir; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This medication contains sodium. Consult your doctor or pharmacist if you are on a salt-restricted diet or if you have a condition that could be worsened by an increase in salt intake (e.g., congestive heart failure).
Older adults may be more sensitive to the side effects of the drug, especially mental/mood changes (such as agitation, confusion).
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
Acyclovir is very similar to valacyclovir. Do not use medications containing valacyclovir while using acyclovir.
If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: change in the amount of urine, seizures, extreme tiredness, loss of consciousness, agitation.
To reduce the risk of spreading genital herpes to others, stop all sexual activity during an outbreak until it is completely healed. At all other times, use effective barrier protections (e.g., latex or polyurethane condoms, dental dams) during all sexual activity. Consult your doctor or pharmacist for more details.
Laboratory and/or medical tests (e.g., kidney function test) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.
For the best possible benefit, it is important to receive each scheduled dose of this medication as directed. If you miss a dose, contact your doctor or pharmacist immediately to establish a new dosing schedule. Do not double the dose to catch up.
Consult the product instructions and your pharmacist for storage details. Keep all medicines away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Information last revised March 2014. Copyright(c) 2014 First Databank, Inc.
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