Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
When these two medicines are taken together, the barbiturate may cause your body to process the blood-thinner more quickly.
What might happen:
The effect of the blood-thinner may decrease.There is an increased chance of bleeding if you are taking these medicines together and you stop taking the barbiturate. You may experience bleeding from your gums, nose bleeds, unusual bruising, or dark stools.
What you should do about this interaction:
Contact your healthcare professionals (e.g. doctor or pharmacist) as soon as possible about taking these two medicines together. If your doctor prescribes these medicines together, you may need to check your bleeding times more often.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
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