If you are:
FDB Contraindicated or Not Recommended: FDA C;RISK OF EARLY PREGNANCY MISCARRIAGE/PREMATURE CLOSURE OF DUCTUS ARTERIOSUS
Precaution: ANIMAL STUDIES SUGGEST EXCRETION OCCURS; INSUFF HUMAN STUDIES DATA AVAILABLE.
An adult over 60:
management or monitoring precaution: Gastrointestinal-Risk for ulceration or serious GI bleed; highest with history of PUD or GI bleed. Renal-Risk for exacerbation of CKD. Cardiovascular-May exacerbate pre-existing hypertension or CHF. Risk of cardiovascular thrombotic events, including MI and stroke. This risk may occur early in treatment and increases with duration of use. Risk for reinfarction with minimal NSAID use post-MI. Contraindicated with CABG. Hepatic-Elevated hepatic transaminases may occur with chronic use.
Giving ketoprofen Capsule, Extended Release Pellets 24 hr to a child under 12:
Severe Precaution: Not recommended. Safety and efficacy not established in pediatrics.