Phenylephrine is a sympathomimetic amine that works by temporarily narrowing the blood vessels in the area. This effect decreases swelling and discomfort. Pramoxine belongs to a class of drugs known as local anesthetics. It works on nerves in the skin to block or reduce the feeling of pain and itching.
Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist. Before use, clean the area with mild soap and water, rinse well, and pat dry.
Apply the product to the skin of the affected area up to 4 times daily, usually in the morning and bedtime, or after each bowel movement, or as directed by your doctor. To apply this product inside the lower part of the anus, use the applicator tip/cap/nozzle. Follow all instructions in the product package, or use as directed by your doctor. Do not apply the product high up inside the rectum.
Dosage is based on your medical condition and response to treatment. Do not use more often or for a longer time than recommended.
If symptoms do not improve within 7 days, if bleeding/worsening pain occurs, or if you think you may have a serious medical problem, consult your doctor promptly.
If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Stop using this medication and tell your doctor right away if any of these rare but very serious side effects occur: fast/irregular heartbeat, pounding headache, nervousness, shakiness (tremor), trouble sleeping.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Before using this product, tell your doctor or pharmacist if you are allergic to phenylephrine; or to pramoxine; or to any of its ingredients; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
If you have any of the following health problems, consult your doctor or pharmacist before using this product: diabetes, heart problems (e.g., chest pain, heart attack), high blood pressure, overactive thyroid (hyperthyroidism), difficult urination due to blockage (e.g., enlarged prostate).
Do not use this product in children 12 years or younger without talking with the doctor.
If you are using this product under your doctor's direction, your doctor or pharmacist may already be aware of possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.
Before using this product, tell your doctor or pharmacist if you use any of the following prescription and nonprescription/herbal products: MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine), drugs to treat high blood pressure (e.g., guanethidine, beta blockers such as metoprolol).
Check the labels on all your medicines (e.g., cough-and-cold products, diet aids) because they may contain ingredients that could increase your heart rate and blood pressure. Ask your pharmacist about using those products safely.
This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
This medicine may be harmful if swallowed. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.
If you are using this product on a regular schedule and miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Store at room temperature at 68-77 degrees F (20-25 degrees C). Different brands of this medication may have different storage needs. Check the product package for instructions on how to store your brand, or ask your pharmacist. Keep all medications away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.Information last revised November 2016. Copyright(c) 2016 First Databank, Inc.
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