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Reglan

Interactions

Atovaquone/Metoclopramide

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

Metoclopramide decreases the amount of atovaquone your body absorbs.

What might happen:

The amount of atovaquone in your blood may decrease and it may not work as well.

What you should do about this interaction:

Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together. Your doctor may want to perform blood tests to see if your medicine is working. Your doctor may want you try a different medicine to prevent vomiting.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

References:

1.Malarone (atovaquone-proguanil) UK summary of product characteristics. GlaxoSmithKline UK August 6, 2012.

2.Malarone (atovaquone and proguanil hydrochloride) US prescribing information. GlaxoSmithKline March, 2010.

3.Barnett ED. Drug-Vaccine & Drug-Drug Interactions. CDC Health Information for International Travel 2014 (The Yellow Book) available at: http://wwwnc.cdc.gov/travel/yellowbook/2014/chapter-2-the-pre-travel-consu ltation/interactions-among-travel-vaccines-and-drugs July 6, 2011.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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