Skip to content
My WebMD Sign In, Sign Up
Novolog Mix 70-30 subcutaneous

Interactions

Antidiabetic Agents/Gatifloxacin

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

How this interaction occurs is not known.

What might happen:

Using gatifloxacin with your diabetes medicine may cause your blood sugar to be too low or too high.

What you should do about this interaction:

Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together. Your doctor may want you to check your blood sugar more often while taking your antibiotic. If you experience a sudden onset of chills, cold sweat, blurred vision, dizziness, drowsiness, shaking, rapid heart rate, weakness, headache, fainting, tingling of the hands or feet, or hunger, check your blood sugar (if possible) and treat yourself for low blood sugar by eating a quick source of glucose such as glucose tablets or gel, table sugar, honey, candy, orange juice, or non-diet soda. Stop using your antibiotic and contact your doctor right away.If you experience pale skin, blurred vision, loss of consciousness, increased thirst, increased urination, fatigue, or fast, deep breathing, check your blood sugar, stop using your antibiotic and contact your doctor right away.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

References:

1.Tequin (gatifloxacin) US prescribing information. Bristol-Myers Squibb Company January, 2006.

2.Dear Canadian Healthcare Professional letter: Subject: Updated safety information for TEQUIN (gatifloxacin) and serious hypoglycemia and hyperglycemia. Bristol-Myers Squibb Canada May 12, 2006.

3.Letourneau G, Morrison B, McMorran M. Gatifloxacin (Tequin): hypoglycemia and hyperglycemia. Canadian Adverse Reaction Newsletter 2003 Jul; 13(2):1-2.

4.Lewis-Hall F. Dear Healthcare Provider letter. Bristol-Myers Squibb February 15, 2006.

5.LeBlanc M, Belanger C, Cossette P. Severe and resistant hypoglycemia associated with concomitant gatifloxacin and glyburide therapy. Pharmacotherapy 2004 Jul;24(7):926-31.

6.Bhasin R, Arce FC, Pasmantier R. Hypoglycemia associated with the use of gatifloxacin. Am J Med Sci 2005 Nov;330(5):250-3.

7.Kesavadev J, Rasheed SA. Gatifloxacin induced abnormalities in glucose homeostasis in a patient on glimepiride. J Assoc Physicians India 2006 Dec;54:951-2.

8.Zvonar R. Gatifloxacin-induced dysglycemia. Am J Health Syst Pharm 2006 Nov 1;63(21):2087-92.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

More about Drugs and Medications

Newsletters

Subscribe to free WebMD newsletters.

  • WebMD Daily

    WebMD Daily

    Subscribe to the WebMD Daily, and you'll get today's top health news and trending topics, and the latest and best information from WebMD.

  • Men's Health

    Men's Health

    Subscribe to the Men's Health newsletter for the latest on disease prevention, fitness, sex, nutrition, and more from WebMD.

  • Women's Health

    Women's Health

    Subscribe to the Women's Health newsletter for the latest on disease prevention, fitness, sex, diet, anti-aging, and more from WebMD.

By clicking Submit, I agree to the WebMD Terms & Conditions & Privacy Policy

URAC: Accredited Health Web Site TRUSTe online privacy certification HONcode Seal AdChoices