How the interaction occurs:
Both of these medicines can each raise the amount of potassium in your body.
What might happen:
Your blood levels of potassium may increase and cause breathing difficulties, chest pain, slow or irregular heartbeat, confusion, or muscle weakness.
What you should do about this interaction:
Make sure your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together. Your doctor may wish to change your medicine or have your potassium level monitored. Let your doctor know if you have any symptoms of a high potassium level.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
1.Bactrim (sulfamethoxazole and trimethoprim) US prescribing information. Mutual Pharmaceutical Company, Inc. June, 2013.
2.Inspra (eplerenone) US prescribing information. Pfizer, Inc. May, 2013.
3.Aldactone (spironolactone) US prescribing information. Pfizer June, 2013.
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