Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Diltiazem, dronedarone or verapamil may slow down how quickly your liver processes tamsulosin.
What might happen:
The amount of tamsulosin in your blood may increase. You may experience a drop in blood pressure which could lead to dizziness, lightheadedness or fainting.
What you should do about this interaction:
Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
1.US Food and Drug Administration (FDA). Drug Development and Drug Interactions: Table of Substrates, Inhibitors and Inducers. Available at: http://www.fda.gov/Drugs/DevelopmentApprovalProcess/DevelopmentResources/D rugInteractionsLabeling/ucm093664.htm. Updated 08/05/2011.
2.This information is based on or an extract from the UW Metabolism and Transport Drug Interaction Database (DIDB) Platform, Copyright University of Washington 1999-2014..
3.Flomax (tamsulosin hydrochloride) US prescribing information. Boehringer Ingelheim Pharmaceuticals, Inc. July, 2014.
4.Michel MC, Bressel HU, Goepel M, Rubben H. A 6-month large-scale study into the safety of tamsulosin. Br J Clin Pharmacol 2001 Jun;51(6):609-14.