Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
These two medicines are taken together to help lower your blood pressure. In some people, they may increase blood pressure. If you stop taking clonidine and continue taking your beta-blocker, or if you stop taking them both at the same time, your blood pressure may also increase.
What might happen:
Your blood pressure may increase to a dangerous level, causing headache, nausea, vomiting, flushing, confusion, tremor, irritability with unrest, or a fast or irregular heartbeat.
What you should do about this interaction:
Contact your healthcare professionals (e.g. doctor or pharmacist) about taking these two medicines together. You may need to check your blood pressure more often when starting or stopping these medicines. They may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first. Follow closely any instructions that your doctor gives you about stopping these medicines.
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