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Tagamet

Interactions

Tacrine/Cimetidine

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

When these two medicines are taken together, cimetidine may prevent your body from processing tacrine properly.

What might happen:

Your blood levels of tacrine may increase and cause toxic effects.

What you should do about this interaction:

If you experience dizziness, unsteadiness, clumsiness, nausea, vomiting, diarrhea, or loss of appetite, contact your doctor. It may be necessary to adjust the dose of your medicine or change you to a different medicine.Your healthcare professionals (e.g. doctor or pharmacist) may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

References:

1.Cognex (tacrine) US prescribing information. Parke-Davis July, 1996.

2.Brunton LL. Agents for control of gastric acidity and treatment of peptic ulcers. In Gilman AG, Rall TW, Nies AS, Taylor P, editors: Goodman and Gilman's The Phamacological Basis of Therapeutics. 8th edition. Elmsford, New York: Pergamon Press, Inc. 1990.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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