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Tofranil-PM

Interactions

Sibutramine/Antidepressants

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Severe. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

Both sibutramine and your antidepressant can affect your central nervous system.

What might happen:

You might have more side effects than normal.

What you should do about this interaction:

Contact your healthcare professionals (e.g. doctor or pharmacist) right away about taking these medicines together. Let your doctor know if you have any side effects from your medicine.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

References:

1.Meridia (sibutramine hydrochloride monohydrate) Canadian prescribing information. Abbott Limited Dec., 2004.

2.Reductil (sibutramine hydrochloride) Australian prescribing information. Abbott Australasia Pty. Ltd. March 5, 2004.

3.Reductil (sibutramine hydrochloride monohydrate) UK summary of product characteristics. Abbott Laboratories, Limited January 12, 2005.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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