If you are:
Only When Necessary:
Precaution: NOT RECOMMENDED BY MFR; MAY DECREASE PROLACTIN LEVELS.
An adult over 60:
management or monitoring precaution: Neuro/Psych-Anticholinergic effects cause sedation, worsen cognitive impairment and increase fall risk. Renal-Decrease dose for CrCL<50 mL/min. Cardiovascular-May cause orthostatic hypotension. Use cautious dosing in heart failure patients. Gastrointestinal-May cause or worsen pre-existing constipation. Genitourinary-Best avoided in patients with urinary retention from any cause.
Giving amantadine to a child under 12:
management or monitoring precaution: Safety and efficacy not established age <1 year.