How the interaction occurs:
When these two medicines are used together, piperacillin may increase the effects of your nondepolarizing muscle relaxant medicine.
What might happen:
The effects of your nondepolarizing muscle relaxant medicine may increase and last for a longer time, causing an increased chance for severe breathing problems.
What you should do about this interaction:
These medicines are used only during surgical procedures or with intensive monitoring in the hospital. If you are to have either inpatient or outpatient surgery, or are to be admitted to a hospital, make sure that all healthcare professionals are aware of all the different medicines that you are taking. This includes prescription and non-prescription medicine, herbal medicines, and nutraceuticals.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
1.Zosyn (piperacillin and tazobactam) US prescribing information. Wyeth Pharmaceuticals September, 2013.
2.Vecuronium bromide prescribing information. Pfizer Inc. February, 2011.