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mannitol (GU irrigant) urethral

Interactions

Tobramycin Inhalation/Selected Diuretics

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

When these two medicines are taken together, the toxic effects of your antibiotic may increase.

What might happen:

You may experience ringing, roaring, a feeling of fullness, or a loss of hearing in the ears; dizziness; or unsteadiness.

What you should do about this interaction:

Tell you doctor if you notice any change in your hearing or balance. Make sure that your doctor knows all of the medicines that you are taking.Contact your healthcare professionals (e.g. doctor or pharmacist) as soon as possible about taking these two medicines together.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

References:

1.Tobi (tobramycin solution for inhalation) US prescribing information. Novartis September. 2013.

2.Lasix (furosemide) US prescribing information. Sanofi-Aventis U.S. LLC March, 2012.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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