Z-Xtra topical precautions What should I know regarding pregnancy, nursing and administering Z-Xtra topical to children or the elderly?If you are: Pregnant: Nursing: Precaution: REPORTS OF INFANT METHEMOGLOBINEMIA AFTER INGESTION OF TOPICAL BENZOCAINE An adult over 60: Precaution: POSSIBLE INCR. CNS/CARDIAC ADVERSE REACTIONS. CONSIDER LOWER DOSE. Giving Z-Xtra topical to a child under 12: Relative Contraindication: INCREASED RISK FOR DEVELOPING METHEMOGLOBINEMIA. CLINICIAN CONSULT ADVISED.