Severe. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
The cause of the interaction is not known.
What might happen:
The risk of toxic effects from your bupropion may increase. Toxic effects may include anxiety, palpitations, agitation, tremors, fainting, dizziness, slowed movements, difficulty urinating, decreased sex drive, drowsiness, or seizures.
What you should do about this interaction:
Contact your healthcare professionals (e.g. doctor or pharmacist) as soon as possible about taking these two medicines together. They may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine without checking with them first.
1.Wellbutrin (bupropion hydrochloride) US prescribing information. GlaxoSmithKline July, 2011.
2.Nardil (phenelzine sulfate) US prescribing information. Parke-Davis May, 2007.
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