Severe. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Amprenavir and fosamprenavir may speed up how quickly your body processes delavirdine.
What might happen:
The amount of delavirdine in your blood may decrease and it may not work as well against your HIV infection.
What you should do about this interaction:
Contact your healthcare professionals (e.g. doctor or pharmacist) about taking these medicines together right away. Your doctor may want to check how well your medicines are working. Your doctor may want to change your medicines.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
1.Agenerase (amprenavir) Oral Solution US prescribing information. GlaxoSmithKline May, 2005.
2.Lexiva (fosamprenavir calcium) US prescribing information. GlaxoSmithKline February, 2013.