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Drugs & Medications

risedronate

RISEDRONATE 75 MG

COMMON BRAND NAME(S): Actonel

GENERIC NAME(S): RISEDRONATE SODIUM

Uses

Risedronate is used to prevent and treat certain types of bone loss (osteoporosis) in adults. Osteoporosis causes bones to become thinner and break more easily. Your chance of developing osteoporosis increases as you age, after menopause, or if you take corticosteroid medications (such as prednisone) for a long time.

This medication works by slowing bone loss to help maintain strong bones and reduces the risk of broken bones (fractures). Risedronate belongs to a class of medications called bisphosphonates.

How to use risedronate

Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start using risedronate and each time you get a refill. Follow the instructions very closely to make sure you absorb as much of the drug as possible and reduce the risk of injury to your esophagus. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth as directed by your doctor, usually once daily for 2 days in a row each month. Take it after getting up for the day and before taking your first food, beverage, or other medication. Do not take it at bedtime or while you are still in bed.

Take this medication with a full glass of plain water (6 to 8 ounces or 180 to 240 milliliters). Do not take it with any other beverage. Swallow the tablet whole. Do not chew or suck on it. Then stay fully upright (sitting, standing, or walking) for at least 30 minutes, and do not lie down until after your first food of the day. Wait at least 30 minutes after taking risedronate before you eat or drink anything other than plain water and before taking any other medication by mouth.

Calcium or iron supplements, vitamins with minerals, antacids containing calcium/magnesium/aluminum, dairy products (such as milk, yogurt), and calcium-enriched juice may interfere with absorption of risedronate. Medications such as quinapril, certain forms of didanosine (chewable/dispersible buffered tablets or pediatric oral solution), sucralfate, and bismuth subsalicylate may also interfere with absorption. Do not take these products for at least 30 minutes after taking risedronate.

Take this medication regularly to get the most benefit from it. It may help to mark your calendar with a reminder every month. Talk to your doctor about the risks and benefits of long-term use of this medication.

Side Effects

Upset stomach may occur. Although uncommon, mild flu-like symptoms (such as fever, tiredness, muscle aches) may occur within several days of taking your first monthly doses, but usually last less than a week. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: increased or severe bone/joint/muscle pain, new or unusual hip/thigh/groin pain, jaw pain, eye/vision problems.

This medication may infrequently cause irritation and ulcers in your stomach or esophagus. Get medical help right away if any of these serious side effects occur: new/severe/worsening heartburn, chest pain, difficult or painful swallowing, severe stomach/abdominal pain, black/tarry stools, vomit that looks like coffee grounds.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking risedronate, tell your doctor or pharmacist if you are allergic to it; or to other bisphosphonates (such as alendronate, etidronate, pamidronate); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: esophagus problems (such as heartburn, narrowing of the esophagus, achalasia), difficult or painful swallowing, low levels of calcium in the blood (hypocalcemia), inability to sit upright or stand for at least 30 minutes, stomach/intestinal disorders (such as ulcers), severe kidney disease.

Infrequently, people taking this class of medication (bisphosphonates) have had serious jawbone problems (osteonecrosis). Lack of proper dental hygiene, poorly fitting dentures, or certain dental procedures (such as tooth extraction, dental surgery) may increase your risk. Medical conditions (such as gum disease/infection, cancer, anemia) might also increase the risk. If you develop jaw pain, tell your doctor and dentist immediately.

Before having any surgery (especially dental procedures), tell your doctor and dentist about this medication and all other products you use (including prescription drugs, nonprescription drugs, and herbal products). Your doctor or dentist may tell you to stop taking risedronate before your surgery. Ask for specific instructions about stopping or starting this medication.

Caution is advised if you are pregnant or planning to become pregnant in the future. This medication may stay in your body for many years. Its effects on an unborn baby are not known. Discuss the risks and benefits with your doctor before starting treatment with risedronate.

It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

Interactions

See also How to Use section.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

This medication may interfere with certain lab tests (bone-imaging agents). Be sure to tell your doctor or laboratory personnel that you are taking this medication.

Overdose

If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Notes

Do not share this medication with others.

Lifestyle changes that help promote healthy bones include increasing weight-bearing exercise, stopping smoking, limiting alcohol, and eating well-balanced meals that contain adequate calcium and vitamin D. Since you may also need to take calcium and vitamin D supplements and make lifestyle changes, consult your doctor for specific advice.

Laboratory and/or medical tests (x-rays, height, blood mineral levels) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

Missed Dose

If you miss a dose when you first get up for the day, do not take it later in the day. If you miss one dose and next month's scheduled doses are more than 7 days away, take the missed dose the next day when you first get up. If you miss both doses and next month's scheduled doses are more than 7 days away, take the doses on the next 2 days when you first get up. Then resume your usual dosing schedule. Do not take more than 2 doses within 7 days.

If you miss one or both doses and next month's scheduled doses are less than 7 days away, skip the missed dose(s) and resume your usual dosing schedule. Do not double the dose to catch up.

If you have any questions, ask your doctor or pharmacist.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Information last revised March 2013. Copyright(c) 2013 First Databank, Inc.

Images

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RISEDRONATE SODIUM 150 MG TAB
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ACTONEL 5 MG TABLET
ACTONEL 5 MG TABLET

Identification

color
yellow
shape
oval
imprint
5 mg, RSN
This medicine is a yellow, oval, film-coated tablet imprinted with "5 mg" and "RSN".
ACTONEL 30 MG TABLET
ACTONEL 30 MG TABLET

Identification

color
white
shape
oval
imprint
RSN, 30 mg
This medicine is a white, oval, film-coated tablet imprinted with "RSN" and "30 mg".
ACTONEL 35 MG TABLET
ACTONEL 35 MG TABLET

Identification

color
orange
shape
oval
imprint
RSN, 35 mg
This medicine is a orange, oval, film-coated tablet imprinted with "RSN" and "35 mg".
ACTONEL 150 MG TABLET
ACTONEL 150 MG TABLET

Identification

color
blue
shape
oval
imprint
RSN, 150 MG
This medicine is a blue, oval, film-coated tablet imprinted with "RSN" and "150 MG".
RISEDRONATE SODIUM 150 MG TAB

Identification

color
light blue
shape
round
imprint
M RE, 150
This medicine is a light blue, round, film-coated tablet imprinted with "M RE" and "150".

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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