Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Both sunitinib and bevacizumab taken together may affect the blood forming components of your body.
What might happen:
Taking sunitinib and bevacizumab together may increase the risk for a rare type of blood disorder.
What you should do about this interaction:
Let your healthcare professionals (e.g. doctor or pharmacist) know right away that you are taking these medications together. Let your doctor know right away if you notice an irregular heartbeat or have any dizziness or fainting episodes.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.Reference:1.Dear Healthcare Provider Letter: Subject: Microangiopathic Hemolytic Anemia (MAHA) in Patients treated with Avastin (bevacizumab) and sunitinib malate. Genetech, Inc. July 11, 2008.