If you are:
FDB Only When Necessary: NO FDA RATING; CASE REPORTS SUGGEST MALFORMATIONS WITH PARENT DRUG IMIPRAMINE
Precaution: LIMITED DATA SUGGEST MINIMAL AMOUNTS EXCRETED WITH NO RISK TO INFANT
An adult over 60:
management or monitoring precaution: Neuro/Psych-Anticholinergic effects may cause sedation, worsen cognitive impairment and increase fall risk. Cardiovascular-May cause orthostatic hypotension at higher doses. Gastrointestinal-May cause or worsen pre-existing constipation. Genitourinary-Best avoided in patients with urinary retention from any cause.
Giving desipramine HCL to a child under 12:
Severe Precaution: Possible increased risk of suicidal ideation and attempt with underlying major depression. Risk of severe cardiovascular adverse events, including sudden death.