Severe. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
When these two medicines are taken together, your body may not process bepridil properly.
What might happen:
The blood levels and effects of bepridil may increase. Toxic effects, such as changes in the rhythm of your heart, may occur.
What you should do about this interaction:
Contact your healthcare professionals (e.g. doctor or pharmacist) as soon as possible about taking these two medicines together. They may already be aware of this drug interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
1.Reyataz (atazanavir sulfate) Australian product information. Bristol-Myers Squibb Pharmaceuticals January 8, 2004.
2.Reyataz (atazanavir) Canadian prescribing information. Bristol-Myers Squibb Canada December 3, 2003.
3.Reyataz (atazanavir sulfate) US prescribing information. Bristol-Myers Squibb Company March, 2015.
4.Norvir (ritonavir) US prescribing information. Abbott Laboratories April, 2010.
5.Aptivus (tipranavir) US prescribing information. Boehringer Ingelheim Pharmaceuticals, Inc. March, 2015.