Severe. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
When these two medicines are taken together, your body may not process your heart medicine properly.
What might happen:
The blood levels of your heart medicine may increase and cause changes in the rhythm of your heart.
What you should do about this interaction:
Contact your healthcare professionals (e.g. doctor or pharmacist) as soon as possible about taking these two medicines together. They may already be aware of this drug interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
1.Kaletra (lopinavir/ritonavir) Canadian prescribing information. Abbott Limited June, 2007.
2.Norvir (ritonavir) US prescribing information. Abbott Laboratories November, 2012.
3.Aptivus (tipranavir) US prescribing information. Boehringer Ingelheim Pharmaceuticals, Inc. February, 2012.