How the interaction occurs:
When cisplatin is given before paclitaxel, the beneficial effects of paclitaxel may be decreased. Cisplatin given before paclitaxel may also change how your body processes paclitaxel. This can result in an increase in its toxic effects.
What might happen:
When paclitaxel is given after cisplatin, the beneficial effects and how your body processes paclitaxel may change.
What you should do about this interaction:
If you experience a persistent sore throat or fever, contact your doctor as soon as possible. The dose of your medicines may need adjusting.When used together, paclitaxel is usually given before cisplatin or at the same time. Your healthcare professionals (e.g. doctor or pharmacist) may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dose of any medicine before checking with them first.
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