This medication is used to treat a certain type of skin condition called rosacea. It helps to reduce the number of pimples and bumps on the face, but it may not decrease redness. It works by reducing skin inflammation caused by rosacea.
Although doxycycline belongs to the class of antibiotics known as tetracyclines, this product does not work as an antibiotic because it does not stop the growth of bacteria. Therefore, do not use this product to treat any infection, including viral infections (such as the common cold, flu). Use this medication only as prescribed by your doctor.
Read the Patient Information Leaflet provided by your pharmacist before you start using this medication and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
This medication is best taken by mouth on an empty stomach, at least 1 hour before or 2 hours after a meal, usually once daily in the morning or as directed by your doctor. Swallow the capsules whole. Do not crush or chew the capsules. Doing so can release all of the drug at once, increasing the risk of side effects.
Take this medication with a full glass of water (8 ounces/240 milliliters) unless directed otherwise. If stomach upset occurs, taking it with food or milk may help. However, doxycycline may not work as well if you take it with food or milk (or anything high in calcium - more details below), so ask your doctor or pharmacist if you may take it that way. Do not lie down for 10 minutes after taking this medication.
Take this medication 2 to 3 hours before or after taking any products containing aluminum, calcium, iron, magnesium, zinc or bismuth subsalicylate. Some examples include antacids, didanosine solution, quinapril, vitamins/minerals, dairy products (such as milk, yogurt), and calcium-enriched juice. These products bind with doxycycline, preventing your body from fully absorbing the drug.
Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Do not skip doses or take more of this medication than prescribed.
Tell your doctor if your condition does not improve or if it worsens.
Upset stomach, nausea, diarrhea, or mild headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.
Tell your doctor right away if you have any serious side effects, including: sunburn (sun sensitivity), difficult/painful swallowing, brown/gray tooth discoloration, blue/gray/brown discoloration of the skin/lips/tongue/gums, unusual tiredness, new signs of infection (e.g., fever, chills, persistent sore throat), change in the amount of urine, pink urine, hearing changes (e.g., ringing in the ears, decreased hearing), easy bruising/bleeding, severe stomach/abdominal pain, persistent nausea/vomiting.
Tetracycline drugs such as doxycycline may rarely cause a serious increase in pressure inside the skull (intracranial hypertension-IH). The risk of this side effect is greater for women of childbearing age who are overweight or who have had IH in the past. If IH develops, it usually goes away after doxycycline is stopped; however, there is a chance of permanent vision loss or blindness. Get medical help right away if you have: persistent/severe headache, vision changes (such as blurred/double vision, decreased vision, sudden blindness), persistent nausea/vomiting.
This medication may rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to a type of resistant bacteria. This condition may occur during treatment or weeks to months after treatment has stopped. Do not use anti-diarrhea products or narcotic pain medications if you have any of the following symptoms because these products may make them worse. Tell your doctor immediately if you develop: persistent diarrhea, abdominal or stomach pain/cramping, blood/mucus in your stool.
Use of this medication for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection (fungal infections). Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or other new symptoms.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, skin lesions/sores, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing, new or worsening swelling/pain in the joints, swollen glands, chest pain, fast/irregular heartbeat.
In the US -
See also Side Effects section.
Before taking doxycycline, tell your doctor or pharmacist if you are allergic to it; or to tetracycline or related drugs (e.g., minocycline); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, problems swallowing, esophagus problems (e.g., hiatal hernia, reflux disease-GERD), stomach surgery (e.g., gastrectomy, gastric bypass surgery), lupus.
This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outdoors.
Before having surgery, tell your doctor or dentist that you are using doxycycline.
Children younger than 8 years may be more sensitive to the side effects of doxycycline, especially tooth discoloration. Tooth discoloration has also occurred in older children and young adults. Discuss the risks and benefits of this medication with the doctor.
This medication is not recommended for use during pregnancy because of possible harm to an unborn baby. Women of child-bearing age should use effective birth control while taking this medication. Consult your doctor for more details. If you become pregnant or think you may be pregnant, tell your doctor immediately.
This medication passes into breast milk in very small amounts. While there have been no reports of harm to nursing infants, consult your doctor before breast-feeding.
See also How to Use section.
Some products that may interact with this drug include: retinoid medications taken by mouth (such as acitretin, isotretinoin), strontium, anti-seizure medications (e.g., carbamazepine, phenobarbital, phenytoin), digoxin, live bacterial vaccines, penicillins, warfarin.
Doxycycline may decrease the effectiveness of hormonal birth control such as pills, patch, or ring. This could cause pregnancy. Be sure to ask your doctor or pharmacist if you should use additional reliable birth control methods while using this medication.
This product can affect the results of certain lab tests. Make sure laboratory personnel and all your doctors know you use this drug.
Do not share this medication with others.
Laboratory and/or medical tests may be performed periodically to check for side effects. Consult your doctor for more details.
Store at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Taking outdated tetracycline-related drugs can result in serious illness. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
Information last revised June 2014. Copyright(c) 2014 First Databank, Inc.
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