Severe. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
When these two medicines are taken together, the effects of one or both medicines may increase.
What might happen:
The side effects related to your NSAID or aspirin may increase (e.g. stomach upset or pain, black or bloody stools, dizziness or drowsiness).
What you should do about this interaction:
Contact your healthcare professionals (e.g. doctor or pharmacist) as soon as possible about taking these two medicines together. They may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.Reference:1.Toradol (ketorolac tromethamine) US prescribing information. Roche Pharmaceuticals March, 2013.