Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Antacids that contain aluminum and/or magnesium may bind to raltegravir in your GI tract.
What might happen:
Your body may not absorb the full dose of your raltegravir and it may not work as well.
What you should do about this interaction:
Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together. Your doctor may want to run some blood tests to check how your medicine is working. If you need an antacid, choose one that contains calcium carbonate instead of aluminum or magnesium. Ask your pharmacist if you need help selecting an antacid.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.Reference:1.Isentress (raltegravir) US prescribing information. Merck & CO., Inc. October, 2013.