Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
When these two medicines are taken together, your body may not process clozapine as quickly.
What might happen:
Your blood levels of clozapine may increase. You may experience a fast heartbeat, low blood pressure, fatigue, dizziness, increased salivation, seizures or decreased breathing.
What you should do about this interaction:
If you experience these problems, contact your doctor right away. The dose of your medicines may be need to be adjusted. Your healthcare professionals (e.g. doctor or pharmacist) may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
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