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    Emtricitabine-tenofovir (TDF) tablet

    precautions

    What should I know regarding pregnancy, nursing and administering Emtricitabine-tenofovir (TDF) tablet to children or the elderly?

    If you are:

    Pregnant:

    Possibly Safe:

    Possibly Safe:

    Nursing:

    Precaution: LIMITED DATA SUGGEST NO KNOWN ADVERSE EFFECTS IN NURSING INFANT

    Absolute Contraindication: CDC DOES NOT RECOMMEND BREASTFEEDING IN HIV-POSITIVE WOMEN.

    An adult over 60:

    management or monitoring precaution: Renal-Adjust dosing interval for CrCL<50mL/min. Fixed dose combinations containing tenofovir are not appropriate if dose adjustment is required. Musculoskeletal-Decreases in bone mineral density have been observed. Consider calcium and vitamin D3 supplementation.

    management or monitoring precaution: Renal- Adhere to manufacturer guidelines for renal impairment and lower CrCL.

    Giving Emtricitabine-tenofovir (TDF) tablet to a child under 12:

    Severe Precaution: Unknown effects on bone development with long term use. Safety and efficacy not established for weight < 17 kg.

    management or monitoring precaution: Risk of lower bone density than expected for developing pediatric patients with tenofovir use. Assess BMD with history of fracture or bone loss. Fixed dose combination may be inappropriate and not indicated with weight < 17 kg.

    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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