If you are:
Precaution: LIMITED DATA SUGGEST NO KNOWN ADVERSE EFFECTS IN NURSING INFANT
Absolute Contraindication: CDC DOES NOT RECOMMEND BREASTFEEDING IN HIV-POSITIVE WOMEN.
An adult over 60:
management or monitoring precaution: Renal-Adjust dosing interval for CrCL<50mL/min. Fixed dose combinations containing tenofovir are not appropriate if dose adjustment is required. Musculoskeletal-Decreases in bone mineral density have been observed. Consider calcium and vitamin D3 supplementation.
management or monitoring precaution: Renal- Adhere to manufacturer guidelines for renal impairment and lower CrCL.
Giving Truvada to a child under 12:
Severe Precaution: Unknown effects on bone development with long term use. Safety and efficacy not established for weight < 17 kg.
management or monitoring precaution: Risk of lower bone density than expected for developing pediatric patients with tenofovir use. Assess BMD with history of fracture or bone loss. Fixed dose combination may be inappropriate and not indicated with weight < 17 kg.