If you are:
Only When Necessary: NON-TERATOGENIC COMPLICATIONS (RESP, GI,CNS) WITH EXPOSURE DURING 3RD TRIMESTER
Precaution: INSUFF DATA; NO IMMEDIATE EFFECTS OBSERVED, LONG TERM CNS EFFECTS UNKNOWN
An adult over 60:
management or monitoring precaution: Hepatic-May need to adjust dose especially in combination with renal impairment. Renal-Avoid use with CrCl < 30 mL/min. Endocrine-Increased risk of SIADH and hyponatremia resulting in an increased risk of falls. Cardiovascular-Elderly may be at increased risk for orthostatic hypotension, syncope and falls.
Giving Duloxetine to a child under 12:
Severe Precaution: Possible increased suicidal ideation and attempt. Monitor height, weight and behavior.
Severe Precaution: Possible increased suicidal ideation and attempt. Risk of anorexia and weight loss. No safety and efficacy.