Lanthanum is used to prevent high blood phosphate levels in patients who are on dialysis due to severe kidney disease. Dialysis removes some phosphate from your blood, but it is difficult to remove enough to keep your phosphate levels balanced. Decreasing blood phosphate levels can help keep your bones strong, prevent unsafe buildup of minerals in your body, and possibly decrease the risk of heart disease and strokes that can result from high phosphate levels. Lanthanum is a natural mineral that works by holding onto phosphate from the diet so that it can pass out of your body.
Read the Medication Guide provided by your pharmacist before you start taking lanthanum carbonate and each time you get a refill. If you have any questions regarding the information, consult your doctor or pharmacist.
Take this medication by mouth with or right after each meal, or as directed by your doctor. This medication must be chewed thoroughly before swallowing to reduce the risk of stomach/abdominal side effects. You may crush the tablets to make it easier to chew them. Do not swallow tablets whole. It is not necessary to swallow this medication with water.
Use this medication regularly in order to get the most benefit from it. Remember to take it after each meal every day, or on the schedule given to you by your doctor. Dosage is based on your medical condition and response to therapy.
Lanthanum may interfere with the absorption of certain other medications taken by mouth (such as warfarin, drugs that interact with antacids). The manufacturer recommends taking these other medications at least 2 hours apart from lanthanum. Talk to your pharmacist for more details (see also the Drug Interactions section).
Tell your doctor right away if any of these serious side effects occur: mental/mood changes, unusual muscle weakness.
Infrequently, serious blockage of the bowels may occur, which may sometimes require surgery or going to the hospital. This can occur especially in people with stomach/abdominal problems (such as abdominal surgery, colon cancer, chronic constipation, slow gut syndrome). Tell your doctor right away if you have severe or persistent stomach/abdominal pain, severe constipation, or persistent vomiting.
A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
In the US -
See also Side Effects section.
Before taking lanthanum, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: stomach/intestinal problems (e.g., ulcers, bowel blockage), mineral imbalance (low level of phosphate in the blood), problems chewing tablets.
This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.
Before having an X-ray of your stomach, be sure to tell X-ray lab personnel that you are taking this medication.
This medication is not recommended for children because of possible effects on the bones.
This medication is not recommended for use during pregnancy. Consult your doctor for more details.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Some products that may interact with this drug include: warfarin.
Because this drug is similar to some antacids, lanthanum may interfere with the absorption of certain drugs in the same way as antacids. Consult your pharmacist for details because you may need to separate taking lanthanum by at least 2 hours from any of the following medications, among others: certain azole antifungals (itraconazole, ketoconazole), certain cephalosporin antibiotics (cefaclor, cefdinir, cefpodoxime), gabapentin, HIV medications (e.g., atazanavir, delavirdine), levothyroxine, mycophenolate, tetracyclines.
Lanthanum may also interfere with the full absorption of other medications (such as quinolone antibiotics including ciprofloxacin/levofloxacin). Talk with your doctor or pharmacist about how to schedule lanthanum and your other medications to prevent this problem.
If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.
Your doctor may direct you to follow a special diet to help lower your blood phosphate levels. Follow the diet closely.
Do not share this medication with others.
Laboratory and/or medical tests (e.g., blood phosphate and calcium levels) should be performed regularly to monitor your progress or check for side effects. Consult your doctor for more details.
If you miss a dose, skip the missed dose unless you have just eaten. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Store at room temperature at 77 degrees F (25 degrees C) away from light and moisture. Brief storage between 59-86 degrees F (15-30 degrees C) is permitted. Do not store in the bathroom. Keep all medicines away from children and pets.
Information last revised November 2013. Copyright(c) 2013 First Databank, Inc.
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