Risedronate is used to prevent and treat certain types of bone loss (osteoporosis) in adults. Osteoporosis causes bones to become thinner and break (fracture) more easily. Your chance of developing osteoporosis increases as you age, after menopause, or if you are taking corticosteroid medications (such as prednisone) for a long time. This medication works by slowing bone loss to help maintain strong bones and reduce the risk of fractures. Risedronate belongs to a class of medications called bisphosphonates.
Calcium is a mineral needed to form healthy bones and to keep them strong. Calcium supplements are used to make sure you get enough calcium in addition to the calcium you get from a well-balanced diet.
Read the Patient Information Leaflet if available from your pharmacist before you start taking this product and each time you get a refill. Follow the instructions very closely to make sure you absorb as much of the drug as possible and reduce the risk of injury to your esophagus. If you have any questions, ask your doctor or pharmacist.
This product package contains both risedronate and calcium tablets. Calcium can decrease the absorption of risedronate if taken within 30 minutes after it. Take risedronate and calcium on separate days to avoid this drug interaction.
For risedronate: Take this medication by mouth as directed by your doctor, usually once a week. Take it after getting up for the day, before taking your first food, beverage, or other medication. Do not take it at bedtime or while you are still in bed. Take this medication with a full glass of plain water (6 to 8 ounces or 180 to 240 milliliters). Do not take it with any other beverages. Swallow the tablet whole. Do not chew or suck on it. Then stay fully upright (sitting, standing, or walking) for at least 30 minutes, and do not lie down until after your first food of the day. Wait at least 30 minutes after taking risedronate before you eat or drink anything other than plain water and before taking any other medication by mouth.
Iron supplements, vitamins with minerals, antacids containing calcium/magnesium/aluminum, dairy products (such as milk, yogurt), and calcium-enriched juice may interfere with absorption of risedronate. Medications such as quinapril, certain forms of didanosine (chewable/dispersible buffered tablets or pediatric oral solution), sucralfate, and bismuth subsalicylate may also interfere with absorption. Do not take these products for at least 30 minutes after taking risedronate.
For calcium: Take the calcium in this product as directed by your doctor, with food for best absorption, usually once daily except for the day you take risedronate. Calcium can interfere with the absorption of other drugs (such as levothyroxine, quinolone antibiotics such as ciprofloxacin, tetracycline antibiotics, iron, estramustine). Ask your pharmacist how and when to take these medications.
Use this product regularly in order to get the most benefit from it. Talk to your doctor about the risks and benefits of long-term use of this medication.
Risedronate may infrequently cause irritation and ulcers in your stomach or esophagus. Get medical help right away if any of these serious side effects occur: new/severe/worsening heartburn, chest pain, difficult or painful swallowing, severe stomach/abdominal pain, black/tarry stools, vomit that looks like coffee grounds.
In the US -
Before taking risedronate with calcium, tell your doctor or pharmacist if you are allergic to either of these drugs; or to other bisphosphonates (such as alendronate, etidronate, pamidronate); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this product, tell your doctor or pharmacist your medical history, especially of: low or high blood calcium levels (hypocalcemia or hypercalcemia), inability to sit upright or stand for at least 30 minutes, esophagus problems (such as narrowing of the esophagus, achalasia), difficult or painful swallowing, kidney problems (such as severe kidney disease, kidney stones), stomach/intestinal disorders (such as ulcers).
Some people taking risedronate may have serious jawbone problems. Your doctor should check your mouth before you start this medication. Tell your dentist that you are taking this medication before you have any dental work done. To help prevent jawbone problems, have regular dental exams and learn how to keep your teeth and gums healthy. If you have jaw pain, tell your doctor and dentist right away.
Before having any surgery (especially dental procedures), tell your doctor and dentist about this medication and all other products you use (including prescription drugs, nonprescription drugs, and herbal products). Your doctor or dentist may tell you to stop taking this medication before your surgery. Ask for specific instructions about stopping or starting this medication.
Caution is advised if you are pregnant or planning to become pregnant in the future. Risedronate may stay in your body for many years. Its effects on an unborn baby are not known. Discuss the risks and benefits with your doctor before starting treatment with risedronate.
It is unknown if risedronate passes into breast milk. Consult your doctor before breast-feeding.
See also How to Use section.
This medication may interfere with certain lab tests (bone-imaging agents). Be sure to tell your doctor or laboratory personnel that you are taking this medication.
If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.
Do not share this product with others.
Lifestyle changes that help promote healthy bones include increasing weight-bearing exercise, stopping smoking, limiting alcohol, and eating well-balanced meals that contain adequate calcium and vitamin D. Since you may also need to take calcium and vitamin D supplements and make lifestyle changes, consult your doctor for specific advice.
Laboratory and/or medical tests (x-rays, height, blood mineral levels) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.
If you miss a dose of risedronate, do not take it later in the day. Take it the next morning after you remember. Take that day's calcium at a later time, with food. Continue taking your weekly dose of risedronate on your originally scheduled day of the week. Do not take two doses on the same day. Consult your doctor or pharmacist if you have any questions.
If you miss a dose of calcium, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose of calcium to catch up unless your doctor directs you otherwise.
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Information last revised March 2015. Copyright(c) 2015 First Databank, Inc.
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