If you are:
FDB Only When Necessary: INSUFF HUMAN DATA;ANIMAL DATA SUGG DEVELOPMENTAL TOXICITY AT 0.2--1 X MRHD
Absolute Contraindication: DRUG EXCRETED IN RAT STUDIES, POTENTIAL FOR IRON DEPLETION IN INFANT.
An adult over 60:
management or monitoring precaution: General-Elderly have increased risk for adverse effects. Renal-Contraindicated with CrCL<40mL/min. Reduce dose by 50% for CrCL=40-60 mL/min. Hepatic-Risk for worsened hepatic impairment and failure. Monitor LFTs closely. Gastrointestinal-GI bleed risk. Hematologic-Caution in high risk myelodysplastic syndromes due to increased incidence of toxicities.
Giving deferasirox Tablet, Dispersible to a child under 12:
management or monitoring precaution: No safety and efficacy established age < 2 years.