Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
How this interaction occurs is not known.
What might happen:
The amount of docetaxel in your blood may increase and cause more side effects than normally expected.
What you should do about this interaction:
Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together. Let your doctor know right away if you have severe vomiting, swelling of the hands/feet/legs, unexplained weight gain, numbness, muscle or joint pain, persistent weakness/fatigue, eye pain, chest pain, black or bloody stools, severe headache, decrease in the amount of urine, or signs of infection such as fever, chills, or persistent sore throat.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.Reference:1.Nexavar (sorafenib tosylate) UK summary of product characteristics. Bayer Plc February 13, 2007.