Severe. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Immunoglobulins may prevent your immune system from properly responding to the vaccine.
What might happen:
The vaccine may not work and you may not develop immunity to the disease it is supposed to prevent.
What you should do about this interaction:
Let your healthcare professionals (e.g. doctor or pharmacist) know if you have any immunoglobulins in the previous year before receiving any vaccination.Let your healthcare professionals (e.g. doctor or pharmacist) know if you have had any vaccinations in the previous month before receiving any immunoglobulin. Your doctor may want to delay the immunoglobulin or repeat the vaccination after you have completed taking immunoglobulin.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
1.WinRho SDF (anti-D (Rho) immunoglobulin (human)) Australian prescribing information. CSL August 30, 2002.
2.Rhophylac (human immunoglobulin anti-D (Rh)) UK prescribing information. ZLB Bioplasma UK Limited December 19, 2003.
3.Rhophylac (Rho human immune globlin) US prescribing information. ZLB Bioplasma Inc. January, 2004.
4.Bayrho-D (immune globulin, Rho(D) human) Canadian prescribing information. Bayer 2004.
5.WinRho SDF (Rho(D) immune globulin intravenous (human)) US prescribing information. Baxter Healthcare Corporation December, 2005.
6.RhoGAM (Rho immune globulin human) US prescribing information. Ortho-Clinical Diagnostics, Inc. November, 2012.