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    calcipotriene-betamethasone topical

    BETAMETHASONE/CALCIPOTRIENE (CALCIPOTRIOL) - TOPICAL

    COMMON BRAND NAME(S): Enstilar, Taclonex

    GENERIC NAME(S): CALCIPOTRIENE/BETAMETHASONE DIPROPIONATE

    Uses

    This medication is used to treat psoriasis. It helps to reduce the redness, thickening, and scaling of the skin that occurs with this condition. Healthy skin lowers your risk for infection and protects you against the environment. This product contains 2 drugs. Betamethasone is a very strong corticosteroid drug that works by decreasing swelling, redness, and itching. Calcipotriene is a form of vitamin D. It is also known as calcipotriol in other countries. It works by slowing down the growth of skin cells so that they don't build up into thickened, scaly skin patches.

    This product should not be used if you have certain types of psoriasis (skin patches with pus-filled blisters, psoriasis over most of your body with intense redness/shedding/oozing). Consult your doctor for more information.

    How to use calcipotriene-betamethasone topical

    Read the Patient Information Leaflet provided by your pharmacist before you start using this product and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

    This medication is for use on the skin only. Apply a thin layer to the affected area(s), usually once daily or as directed by your doctor. Rub it in gently and completely. Wash your hands after using, unless you are using this medication to treat the hands. Avoid getting any medication in the eyes or mouth. If this occurs, rinse right away with water. Do not apply this product to the face, underarms, or groin area. Do not use this medication for more than 4 weeks unless directed by your doctor.

    If you are using the ointment, because of the increased risk of side effects, adults should not use more than 100 grams of the ointment per week unless directed and closely monitored by the doctor. Also, children and teenagers should not use more than 60 grams of the ointment per week.

    If you are using the foam, shake the can before using. Do not use more than 60 grams of the foam every 4 days.

    Do not bandage, wrap, or cover the treated area unless your doctor instructs you to do so. Do not apply this medication to large areas of damaged skin or use it in skin folds. Do not apply more of this medication than prescribed or use it more often or for longer than directed. Doing so may increase the amount of medication that is absorbed into your bloodstream, an effect that may increase your risk of side effects.

    Inform your doctor if your condition does not improve or if it worsens. It may take a week to see any improvement and 4 weeks to see the full benefit of this medication.

    Side Effects

    Itching, burning, redness, or irritation of the skin may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

    Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

    Tell your doctor right away if you have any serious side effects, including: skin thinning/discoloration/"stretch marks", swelling/inflammation of the hair pores (folliculitis), worsening of psoriasis.

    This product may rarely cause an increase in the level of calcium in your blood. Tell your doctor right away if you notice any of the following unlikely but serious side effects: mental/mood changes, unexplained constipation.

    Rarely, it is possible this medication will be absorbed from the skin into the bloodstream. This can lead to side effects of too much corticosteroid. These side effects are more likely in children, and in people who use this medication for a long time or over large areas of the skin. Tell your doctor right away if any of the following side effects occur: unusual/extreme tiredness, weight loss, headache, swelling ankles/feet, increased thirst/urination, vision problems.

    A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

    This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

    In the US -

    Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

    In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

    Precautions

    Before using this product, tell your doctor or pharmacist if you are allergic to betamethasone or calcipotriene; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

    Before using this medication, tell your doctor or pharmacist your medical history, especially of: a certain mineral imbalance (high calcium blood level), thin skin in the areas to be treated.

    If you have a skin infection or a skin reaction other than psoriasis (such as bacterial skin infection, chickenpox, herpes simplex), it should be treated before you start this medication. Betamethasone and other corticosteroid drugs can slow down your body's response to antibiotic drugs and make it more difficult to clear an infection.

    This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outdoors. Your doctor may direct you to limit or avoid phototherapy while you use this product. Discuss this further with your doctor.

    Rarely, using corticosteroid medications for a long time or over large areas of skin can make it more difficult for your body to respond to physical stress. Therefore, before having surgery or emergency treatment, or if you get a serious illness/injury, tell your doctor or dentist that you are using this medication or have used this medication within the past few months.

    Though it is unlikely, this medication may slow down a child's growth if used for a long time. The effect on final adult height is unknown. See the doctor regularly so your child's height can be checked.

    During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

    It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

    Interactions

    Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

    Some products that may interact with this drug include: other corticosteroids (such as prednisone, hydrocortisone), other products containing calcipotriene (calcipotriol).

    Overdose

    This medicine may be harmful if swallowed. If swallowing or overdose is suspected, contact a poison control center or emergency room right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

    Notes

    Do not share this medication with others.

    Lab and/or medical tests (such as adrenal gland function tests) may be done while you are using this medication, especially if you use it for an extended period of time or apply it over large areas of the body. Consult your doctor for more details.

    Try to identify and reduce the triggers that may worsen your psoriasis (such as stress, skin injury). Discuss with your doctor additional ways to control symptoms, such as using a moisturizer to treat dry, itching skin.

    Missed Dose

    If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.

    Storage

    Store the US ointment in its tightly capped tube at room temperature.

    Store the Canadian ointment in the refrigerator or at room temperature between 41-77 degrees F (5-25 degrees C). However, refrigerating the product may make it more difficult to apply. If you are using this product on delicate skin, it is best to store this medication at room temperature so it is easier to rub it in. Check the product instructions about how long you may store the tube once it is opened.

    Store the foam at room temperature. Do not freeze. The foam is flammable. Avoid smoking during and right after applying the foam. Do not puncture the foam can or expose to high heat or open flame. Use the foam within 6 months after first opening the can.

    Keep all medications away from children and pets.

    Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

    Information last revised January 2016. Copyright(c) 2016 First Databank, Inc.

    Images

    ENSTILAR 0.005%-0.064% FOAM
    ENSTILAR 0.005%-0.064% FOAM
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    ENSTILAR 0.005%-0.064% FOAM
    ENSTILAR 0.005%-0.064% FOAM

    Identification

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    This medicine is a white foam.

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    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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