This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug, changing your diet or commencing any course of treatment.
Important. Possible changes in your diet, medicine, or dosage should be discussed with your doctor or pharmacist.
How the interaction occurs:
Your medicine and tryptophan-containing foods both increase the amount of serotonin in your body.
What might happen:
Extremely high serotonin levels may cause changes in body temperature, blood pressure and behavior, leading to a medical condition called Serotonin Syndrome. Serotonin Syndrome may be life threatening. This effect has been reported with tryptophan supplements, not with foods high in tryptophan.
What you should do about this interaction:
Tryptophan is an essential amino acid and cannot be eliminated completely from the diet. If you are experiencing mild side effects from your medicine, discuss with your health care professional (e.g. doctor or pharmacist) if you may benefit from the limiting the amounts of foods that are high in tryptophan that you consume during a single meal. Foods high in tryptophan include chocolate, oats, dried dates, dairy products, red meats, eggs, fish, shellfish, poultry, seeds (sesame, chickpeas, sunflowers, pumpkin), greens, bananas, peanuts, and spirulina.If you experience muscle twitching, tremors, shivering and stiffness, fever, heavy sweating, heart palpitations, restlessness, confusion, agitation, trouble with coordination, or severe diarrhea contact your doctor right away.Contact your healthcare professional for more information, including recommendations for your diet.Your healthcare professionals may be aware of this interaction and may be monitoring you for it. Do not start, stop, or change your medicine or diet before checking with them first.
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