Linagliptin/Strong P-gp or CYP3A4 Inducer
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Your medicine may speed up how quickly your body processes linagliptin.
What might happen:
The amount of linagliptin in your blood may decrease and it may not work as well at treating your diabetes.
What you should do about this interaction:
Make sure your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together or if you have used carbamazepine, phenytoin, rifampin, St. John's wort, or tipranavir in the previous six weeks. Your doctor may want to change your diabetes medicine or have you monitor your blood sugars more closely during your therapy and for several weeks after completing therapy with your other medicine.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.Reference:1.Tradjenta (linagliptin) US prescribing information. Boehringer Ingelheim International GmbH September, 2012.