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Invirase Oral

Vardenafil/Selected Protease Inhibitors

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

Some protease inhibitors may slow down how quickly your liver processes vardenafil.

What might happen:

Your blood levels of vardenafil may increase and cause harmful effects.

What you should do about this interaction:

Contact your healthcare professionals (e.g. doctor or pharmacist) if you experience a painful or prolonged erection, changes in vision, or dizziness. Your doctor may want to change your dose of vardenafil.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

References:

1.Levitra (vardenafil hydrochloride) Canadian prescribing information. Bayer, Inc. October 24, 2006.
2.Reyataz (atazanavir sulfate) US prescribing information. Bristol-Myers Squibb Company January, 2013.
3.Prezista (darunavir) US prescribing information. Tibotec Inc. February, 2013.
4.Lexiva (fosamprenavir calcium) US prescribing information. GlaxoSmithKline February, 2013.
5.Viracept (nelfinavir mesylate) US prescribing information. Agouron Pharmaceuticals, Inc. April, 2012.
6.Fortovase (saquinavir) US prescribing information. Roche Laboratories, Inc. December, 2004.
7.Invirase (saquinavir mesylate) US prescribing information. Roche Laboratories, Inc. February, 2012.
8.Aptivus (tipranavir) US prescribing information. Boehringer Ingelheim Pharmaceuticals, Inc. February, 2012.

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