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Effient oral

Important Note

Warnings
Uses
Side Effects
Precautions
Interactions
Overdose
Effient oral Warnings

Prasugrel can rarely cause very serious (possibly fatal) bleeding. Tell your doctor right away if you notice any signs of serious bleeding. See also Side Effects and Precautions sections.

Effient oral Uses

Prasugrel is used with aspirin by patients with heart disease (recent heart attack, unstable angina) who undergo a certain heart procedure (angioplasty). This medication helps to prevent other serious heart/blood vessel problems (such as heart attacks, strokes, blood clots in stents). It works by blocking platelets from sticking together and forming harmful blood clots. This "anti-platelet" effect helps to keep blood flowing smoothly in your body.

How to use Effient oral

Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start taking prasugrel and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor, usually once a day. Your doctor may direct you to take this medication with low-dose aspirin (usually at dosages of 81-325 milligrams a day). Follow your doctor's instructions carefully.

It is very important to take prasugrel exactly as directed. Do not increase your dose or take this medication more often than prescribed. Your condition will not improve any faster, and your risk of side effects will increase. Also, do not stop using this medication unless directed by your doctor.

The dosage is based on your medical condition, weight, and response to treatment.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.

Effient oral Side Effects

Headache, nausea, nosebleed, and stomach upset may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

This medication can cause serious bleeding. Tell your doctor right away if you have any signs of serious bleeding, including: unusual pain/swelling/discomfort, unusual bruising, prolonged bleeding from cuts or gums, persistent/frequent nosebleeds, unusually heavy/prolonged menstrual flow, coughing up blood, bloody/black/tarry stools, bloody urine, vomit that is bloody or looks like coffee grounds, severe headache, dizziness/fainting, shortness of breath, chest pain, difficulty swallowing.

Prasugrel has rarely caused a certain blood disorder (thrombotic thrombocytopenic purpura). Get medical help right away if you develop symptoms of this blood disorder, including: vision changes, slurred speech, confusion, yellowing eyes/skin, dark urine, change in the amount of urine, unusual weakness/tiredness, unexplained fever.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: severe rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Effient oral Precautions

Before taking prasugrel, tell your doctor or pharmacist if you are allergic to it; or to other thienopyridines (such as clopidogrel); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood disorders (such as hemophilia), bleeding problems (such as bleeding of the stomach/intestines, bleeding in the brain), blood clots in the brain (stroke, transient ischemic attack-TIA), recent major injury/surgery, liver disease, stomach/intestinal ulcers.

Before having surgery or any medical/dental procedures (including heart bypass surgery-CABG), tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

This medicine may cause stomach bleeding. Limit alcohol while taking this drug because it may increase the risk of stomach bleeding.

Older adults (75 years or older) may be more sensitive to the side effects of this drug, especially bleeding. Discuss the risks and benefits with your doctor.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Effient oral Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

A product that may interact with this drug is: tipranavir.

This medication is sometimes used together with other drugs that have "blood thinning" or anti-platelet effects, such as aspirin or heparin. When these combinations are prescribed by your doctor, you will require closer monitoring to minimize your risk of bleeding. Keep all medical and laboratory appointments.

Check all prescription and nonprescription medicine labels carefully since many medications contain pain relievers/fever reducers (aspirin, NSAIDs such as ibuprofen, naproxen) that may increase your risk for bleeding if taken together with this medication. However, if your doctor has directed you to take low-dose aspirin to prevent heart attack or stroke (usually at dosages of 81-325 milligrams a day), you should continue taking it unless your doctor instructs you otherwise. Ask your doctor or pharmacist for more details.

Effient oral Overdose

If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

NOTES:

Do not share this medication with others.

Laboratory and/or medical tests (such as complete blood count) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

MISSED DOSE:

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

STORAGE:

Store at room temperature away from light and moisture. Store the medication in the original bottle with the desiccant to protect against moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

MEDICAL ALERT: Your condition can cause complications in a medical emergency. For information about enrolling in MedicAlert, call 1-888-633-4298 (US) or 1-800-668-1507 (Canada).

Information last revised November 2013. Copyright(c) 2013 First Databank, Inc.

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