Cyclosporine/Azole Antifungal Agents
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
The cause of this interaction is not known. Antifungal medicines may change the way your body processes cyclosporine.
What might happen:
Your blood levels of cyclosporine may increase and cause toxic effects that may harm your kidneys.
What you should do about this interaction:
Make sure that your doctor knows all of the medicines that you are taking.Tell your doctor if you have any kidney problems. If you experience any shortness of breath, unusual swelling, changes in the color or amount of your urine, or changes in how often you urinate, contact your doctor. Your cyclosporine blood levels may need to be checked and the dosage adjusted when you first start or stop taking the antifungal medicine.Your healthcare professionals (e.g. doctor or pharmacist) may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
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