Exemestane/St. John's Wort
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
St. John's wort may speed up how quickly your liver processes exemestane.
What might happen:
The amount of exemestane in your blood may decrease and it may not work as well.
What you should do about this interaction:
Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking St. John's wort and if you stop taking St. John's wort. Your doctor may want to change the dose of your exemestane while you are taking St. John's wort.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.Reference:1.Aromasin (exemestane) US prescribing information. Pharmacia & Upjohn Company February, 2013.