Selected Theophylline Derivatives/Moricizine
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Moricizine may speed up how quickly your liver processes theophylline.
What might happen:
The amount of theophylline in your blood may decrease and cause breathing problems
What you should do about this interaction:
Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together. Your doctor may want to check your theophylline level more often. If you experience problems with your breathing or other effects, contact your doctor. You doctor may need to change the dose of your medicine.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.Reference:1.Pieniaszek HJ Jr, Davidson AF, Benedek IH. Effect of moricizine on the pharmacokinetics of single-dose theophylline in healthy subjects. Ther Drug Monit 1993 Jun;15(3):199-203.