Skip to content
My WebMD Sign In, Sign Up

Provocholine inhalation

Important Note

Common Brand Name(s): Provocholine

Warnings
Uses
Side Effects
Precautions
Interactions
Overdose
Provocholine inhalation Warnings

This medication must be used in a hospital or clinic setting under close medical supervision. It is only to be used for testing (challenge test) and should not be used to treat any conditions.

Emergency equipment and medications must be available to reverse the effects of methacholine if you experience any breathing difficulties during or after the test.

This drug is not recommended for use if you already have asthma, wheezing, or poor lung function test results before this challenge test.

Provocholine inhalation Uses

Methacholine is used as a test to determine whether you may have asthma. It is a cholinergic drug that causes wheezing and shortness of breath.

How to use Provocholine inhalation

This medication is to be inhaled only with a special breathing device (nebulizer) under the direct supervision of a health care professional in a hospital or clinic setting. Do not take this medication by mouth or by injection.

This product must be diluted before being inhaled. Before using this product, check it visually for particles or discoloration. If either is present, do not use the liquid. Use a filter when putting this medication into the nebulizer.

Tell the health care professional if you develop any trouble breathing at any time during the test.

The dosage is based on your medical condition and response to treatment.

Provocholine inhalation Side Effects

Headache, sore throat, lightheadedness, nausea, vomiting, or dizziness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these serious side effects occur: trouble breathing, cough, wheezing, chest pain/tightness, irregular heartbeat.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Provocholine inhalation Precautions

Before using methacholine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: asthma.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: seizures, heart disease, thyroid disease, trouble urinating (urinary obstruction), stomach ulcers, seasonal allergies/"hay fever" (allergic rhinitis), history of being exposed to air pollutants, recent/current flu, other lung disease (e.g., cystic fibrosis, chronic obstructive pulmonary disease-COPD).

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

Provocholine inhalation Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: beta-blockers (e.g., nadolol, propranolol), asthma drugs (e.g., quick relief inhalers such as albuterol, steroid inhalers such as fluticasone, triamcinolone).

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

Provocholine inhalation Overdose

If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: fainting, loss of consciousness, chest pain, heart attack.

NOTES:

Do not share this medication with others.

Lung function test will be done before, during, and after using this product.

MISSED DOSE:

Not applicable.

STORAGE:

Before mixing, store the dry powder and mixing solution at room temperature between 59-86 degrees F (15-30 degrees C) away from light. Once mixed, the solution is good for up to 14 days and may be refrigerated at 36-46 degrees F (2-8 degrees C). Some preparations must be mixed on the day of the test. Discard any unused portion of the vials. Keep all medicines away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

Information last revised March 2013. Copyright(c) 2013 First Databank, Inc.

Be the first to share your experience with this drug.

Review this Treatment

Find a Drug:

by name or medical condition or shape/color (Pill Identifier)

(for example: aspirin)

(for example: diabetes)

Report Problems to the Food and Drug Administration
 
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Ask the pharmacist

Questions about medications? Get expert answers by video or live chat about allergies, pregnancy, sleep, and more.
See the Ask the Pharmacist event schedule.

Ask a Question

Popular Slideshows & Tools on WebMD

hands on abdomen
Can you catch one?
Woman sitting in front of UV lights
Is yours working?
woman using breath spray
What's causing yours?
womans hand on abdomen
Are you ready for baby?
MS Overview
Recognizing symptoms.
bowl of yogurt with heart shape
Eat for a healthy heart.
woman doing pushups
To help you get fit.
Colored x-ray of tooth decay
Know what to look for.
Woman sitting with child
Do you know the symptoms?
mosquito
Stings, bites, burns, and more.
Allentown, PA
Are you living in one?
Thyroid exam
See how much you know.

Women's Health Newsletter

Find out what women really need.

WebMD the app

Get trusted health information. Whenever. Wherever... with your iPhone, iPad or Android.

Find Out More

IMPORTANT: About This Section and Other User-Generated Content on WebMD

The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. Some of these opinions may contain information about treatment or uses of drug products that have not been approved by the U.S. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment.

Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately.