This medication is a combination of carisoprodol, aspirin, and codeine. It provides temporary relief of pain and discomfort from muscle injuries such as strains, sprains, and spasms. It is usually used along with rest, physical therapy, and other treatments.

Carisoprodol relaxes tight muscles and relieves pain, cramping, and stiffness so you can move around more and get back to doing your daily activities. Carisoprodol belongs to a class of drugs called muscle relaxants. Aspirin helps decrease pain and swelling. Codeine is a narcotic pain reliever.

Take this medication by mouth, usually 4 times a day or as directed by your doctor.

Take this medication with a full glass of water (6 to 8 ounces/180 to 240 milliliters). Do not lie down for at least 30 minutes after taking this drug.

If you have nausea, you may take this drug with food, although this may cause your body to absorb less of the drug and get less benefit from it. Consult your doctor or pharmacist about other ways to decrease nausea (e.g., antihistamines, lying down for 1-2 hours with as little head movement as possible).

The dosage is based on your medical condition and response to treatment. If you are extremely drowsy after using this medication, consult your doctor or pharmacist promptly. Your dosage may need to be lowered. Pain medications work best if they are used as the first signs of pain occur. If you wait until the symptoms have worsened, the medication may not work as well.

This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses. In such cases, withdrawal symptoms (such as nausea, diarrhea, stomach cramps) may occur if you suddenly stop using this medication. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Consult your doctor or pharmacist for more details, and report any withdrawal reactions immediately.

Though very unlikely, abnormal drug-seeking behavior (addiction) is possible with this medication. Do not increase your dose, take it more frequently, or take it for a longer time than prescribed. Properly stop the medication when so directed.

When used for an extended period, this medication may not work as well and may require different dosing. Talk with your doctor if this medication stops working well.

Tell your doctor if your condition persists or worsens.

Nausea, vomiting, constipation, lightheadedness, dizziness, drowsiness, stomach upset, headache, or flushing may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

To prevent constipation, maintain a diet adequate in fiber, drink plenty of water, and exercise. If you become constipated while using this drug, consult your pharmacist for help in selecting a laxative (e.g., stimulant-type with stool softener).

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur: slow/shallow breathing, fainting, hearing problems, difficult/painful swallowing, difficult urination, fast heartbeat, change in the amount/color of urine, easy bleeding/bruising.

Sometimes carisoprodol may cause a very rare but serious reaction that occurs within minutes or hours of the first dose of this medication. Stop taking this medication and seek immediate medical attention if any of these symptoms occur: unable to move arms/legs, shaky/unsteady movement, loss of balance, joint pain, mental/mood changes (e.g., agitation, confusion, unexplained mood swings), vision problems (e.g., blurred vision, double vision, loss of vision), extreme weakness.

The aspirin in this product may rarely cause very serious (possibly fatal) bleeding in the stomach/intestines. Seek immediate medical attention if you notice any of these rare but very serious side effects: severe stomach/abdominal pain, black/bloody/tarry stools, vomit that looks like coffee grounds, unexplained weight loss.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Before taking this medication, tell your doctor or pharmacist if you are allergic to carisoprodol, codeine, or aspirin; or to related medications such as meprobamate, tybamate, other narcotics such as hydrocodone, NSAIDs such as ibuprofen or naproxen, or other salicylates such as salsalate; or if you have any other allergies.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: aspirin-sensitive asthma (a history of worsening breathing with runny/stuffy nose after taking aspirin or other NSAIDs), bleeding/blood clotting problems, certain genetic blood disorder (porphyria), severe breathing problems, serious stomach/intestinal problems (e.g., ulcers, bleeding, blockage), intoxication with alcohol or medications that depress the nervous system or your breathing (CNS/respiratory depressants such as tranquilizers/sedatives).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: adrenal gland problem (e.g., Addison's disease), brain disorders (e.g., seizures, head injury, tumor, increased intracranial pressure), personal/family history of regular use/abuse of drugs/alcohol, gallbladder disease, gout, growths in the nose (nasal polyps), heart problems (e.g., fast/irregular heartbeat, heart failure), high blood pressure, kidney disease, liver disease, lung diseases (e.g., asthma, chronic obstructive pulmonary disease), mental/mood disorders (e.g., toxic psychosis), disease of the pancreas (e.g., pancreatitis), a certain spinal problem (kyphoscoliosis), other stomach problems (e.g., acid-reflux disease, heartburn), difficulty urinating (e.g., due to enlarged prostate or urethral narrowing), underactive thyroid (hypothyroidism).

This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.

To avoid dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

This medicine may cause stomach bleeding. Daily use of alcohol and tobacco, especially when combined with this medicine, may increase your risk for stomach bleeding. Limit alcohol and stop smoking. Consult your doctor or pharmacist for more information.

This medication contains aspirin. Children and teenagers should not take aspirin if they have chickenpox, flu, or any undiagnosed illness without first consulting a doctor about Reye's syndrome, a rare but serious illness.

Caution is advised when using this drug in the elderly because they may be more sensitive to its effects, especially slow/shallow breathing, dizziness, drowsiness, and stomach/intestinal bleeding.

This medication is not recommended for use during pregnancy. It may harm an unborn baby. Discuss the risks and benefits with your doctor. Infants born to mothers who have used this medication for an extended time may have withdrawal symptoms such as irritability, abnormal/persistent crying, vomiting, or diarrhea. Tell your doctor immediately if you notice any of these symptoms in your newborn.

This drug may pass into breast milk and could have undesirable effects on a nursing infant. Therefore, breast-feeding is not recommended while using this drug. Consult your doctor before breast-feeding.

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.

This drug should not be used with the following medications because very serious interactions may occur: cidofovir, ketorolac, mifepristone, flu vaccine inhaled through the nose, narcotic blockers (e.g., naltrexone), pramlintide.

If you are currently using any of the medications listed above or have received the flu vaccine in the last month, tell your doctor or pharmacist before using this product.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: anticholinergic drugs (e.g., atropine, belladonna alkaloids, scopolamine), certain anti-Parkinson's drugs (e.g., benztropine, trihexyphenidyl), anti-platelet drugs (e.g., clopidogrel), "blood thinners" (e.g., heparin, warfarin), bisphosphonates taken by mouth (e.g., alendronate), carbonic anhydrase inhibitors (e.g., acetazolamide), cimetidine, corticosteroids (e.g., prednisone), cyclosporine, drugs for diabetes (e.g., insulin, sulfonylureas such as glipizide), drugs for gout (e.g., probenecid, sulfinpyrazone), drugs for high blood pressure (e.g., ACE inhibitors such as captopril/lisinopril, angiotensin II receptor blockers such as as losartan, and beta blockers such as metoprolol), drugs that change the acidity of urine (e.g., antacids, citrates, sodium bicarbonate, high doses of vitamin C/ascorbic acid), ginkgo biloba, lithium, methotrexate, narcotic agonist/antagonists (e.g., butorphanol, nalbuphine), NSAIDs and other salicylates (e.g., ibuprofen, naproxen, salsalate), pemetrexed, potassium tablets/capsules, quinidine, SSRI antidepressants (e.g., fluoxetine, paroxetine), "water pills" (diuretics such as furosemide, hydrochlorothiazide).

Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., diphenhydramine), anti-seizure drugs (e.g., carbamazepine), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., hydrocodone, propoxyphene), psychiatric medicines (e.g., chlorpromazine, risperidone, amitriptyline, trazodone). Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.

Check all prescription and nonprescription medicine labels carefully since many contain pain relievers/fever reducers (NSAIDs such as ibuprofen, naproxen, or aspirin) that are similar to this drug. Low-dose aspirin should be continued if prescribed by your doctor for heart attack or stroke prevention (usually at dosages of 81-325 milligrams a day). Consult your doctor or pharmacist for more details.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms may include: ringing in ears, confusion, fast/irregular heartbeat, seizures, and loss of consciousness.

Do not share this medication with others. It is against the law.

This medication has been prescribed for your current condition only. Do not use it later for another condition unless told to do so by your doctor. A different medication may be necessary in that case.

Laboratory and/or medical tests (e.g., complete blood count, kidney/liver tests) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Store at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

Information last revised July 2009 Copyright(c) 2009 First DataBank, Inc.