Quinidine/Urinary Alkalinizers
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Medical warning:
Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
When these two medicines are taken together, your body may process quinidine more slowly.
What might happen:
The quinidine levels in your blood may increase and cause an irregular heartbeat.
What you should do about this interaction:
If you experience an irregular heartbeat, contact your doctor. It may be necessary to adjust your dose of quinidine.Your healthcare professionals (e.g. doctor or pharmacist) may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
References:
1.Gerhardt RE, Knouss RF, Thyrum PT, Luchi RJ, Morris JJ Jr. Quinidine excretion in aciduria and alkaluria. Ann Intern Med 1969 Nov;71(5):927-33.
2.Knouss RF, Gebhardt RE, Thyrum PT, Luchi RJ, Morris JJ. Variation in quinidine excretion with changing urine pH. Ann Intern Med 1968 May; 68(5):1968 May.





