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Drugs & Medications A-Z

Panafil Top

Back to Drug Overview

Collagenase; Papain/Topical Heavy Metals

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

Heavy metals, such as lead, mercury, and silver, which are contained in some antiseptics and other topical products, may inactivate collagenase and papain.

What might happen:

Your collagenase or papain may not work as well in treating your wound.

What you should do about this interaction:

Avoid applying products that contain lead, mercury, or silver to the same wound area to which you are applying collagenase or papain. If you have any questions, contact your healthcare professional (e.g. doctor or pharmacist).Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

References:

1.Santyl (collagenase) US prescribing information. Ross Products Division, Abbott Laboratories, Inc. December, 2003.
2.Accuzyme (papain, urea) ointment US prescribing information. Healthpoint, Ltd. November, 2004.
3.Accuzyme (papain, urea) spray US prescribing information. Healthpoint, Ltd. March, 2004.
4.Ethezyme, Ethezyme 830 (papain, urea) ointment US prescribing information. Ethex Corporation July, 2004.
5.Gladase (papain, urea) ointment US prescribing information. Smith & Nephew, Inc. March, 2005.
6.Gladase-C (papain, urea) ointment US prescribing information. Smith & Nephew, Inc. March, 2005.
7.Kovia (papain, urea) ointment US prescribing information. Stratus Pharmaceuticals Inc. December, 1999.
8.Panafil (papain, urea, chlorophylin copper complex sodium) ointment US prescribing information. Healthpoint, Ltd. December, 2004.
9.Panafil (papain, urea, chlorophylin copper complex sodium) ointment US prescribing information. Healthpoint, Ltd. March, 2004.
10.Ziox (papain, urea, chlorophylin copper complex sodium) ointment US prescribing information. Stratus Pharmaceuticals Inc. August, 2000.

See 7 Reviews for this Drug. - OR -

Related to Panafil Top

Conditions & Treatments Related to Panafil Top

Bed Sore Medications

Removal of Dead or Infected Tissue from Wound Medications

Venous Ulcers Medications

Burn Medications

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