Eletriptan/Selected Macrolide Antibiotics
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Medical warning:
Severe. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Certain antibiotics may slow down how quickly your liver processes eletriptan.
What might happen:
The amount of eletriptan in your body may increase and cause unwanted side effects such as high blood pressure, a rapid heart beat, chest pain, sweating, nausea, or dizziness.
What you should do about this interaction:
Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together. Your doctor may want to change one of the medicines that you are taking. If you notice any extra side effects from your eletriptan while taking your antibiotic, let your doctor know.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
References:
1.Relpax (eletriptan hydrobromide) UK summary of product characteristics. Pfizer Limited June 13, 2001.
2.Relpax (eletriptan hydrobromide) US prescribing information. Pfizer Inc. April, 2011.





