Skip to content
My WebMD Sign In, Sign Up

Aerolate 111 oral

Beta-Blockers/Theophyllines

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

When these two medicines are taken together, your body may not process theophylline properly. Your beta-blocker may interfere with the benefits of theophylline.

What might happen:

The effects of your theophylline may decrease and cause breathing problems.

What you should do about this interaction:

If you experience problems with your breathing or other effects, contact your doctor. It may be necessary to adjust the dose of your medicine or change you to a different beta-blocker. Cigarette smoking may make this interaction worse.Your healthcare professionals (e.g. doctor or pharmacist) may already be aware of this drug interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

References:

1.Horvath JS, Woolcock AJ, Tiller DJ, Donnelly P, Armstrong J, Caterson R. A comparison of metoprolol and propranolol on blood pressure and respiratory function in patients with hypertension. Aust N Z J Med 1978 Feb;8(1):1-6.
2.Mue S, Sasaki T, Shibahara S, Takahashi M, Ohmi T, Yamauchi K, Suzuki S, Hida W, Takishima T. Influence of metoprolol on hemodynamics and respiratory function in asthmatic patients. Int J Clin Pharmacol Biopharm 1979 Aug;17(8):346-50.
3.Conrad KA, Nyman DW. Effects of metoprolol and propranolol on theophylline elimination. Clin Pharmacol Ther 1980 Oct;28(4):463-7.
4.Kearney TE, Manoguerra AS, Curtis GP, Ziegler MG. Theophylline toxicity and the beta-adrenergic system. Ann Intern Med 1985 Jun;102(6):766-9.
5.Miners JO, Wing LM, Lillywhite KJ, Robson RA. Selectivity and dose-dependency of the inhibitory effect of propranolol on theophylline metabolism in man. Br J Clin Pharmacol 1985 Sep;20(3):219-23.
6.Farrar KT, Dunn AM. Beta-blockers in treatment of theophylline overdose. Lancet 1985 Apr 27;1(8435):983.
7.Amin DN, Henry JA. Propranolol administration in theophylline overdose. Lancet 1985 Mar 2;1(8427):520-1.
8.Lombardi TP, Bertino JS Jr, Goldberg A, Middleton E Jr, Slaughter RL. The effects of a beta-2 selective adrenergic agonist and a beta- nonselective antagonist on theophylline clearance. J Clin Pharmacol 1987 Jul; 27(7):523-9.
9.Cerasa LA, Bertino JS Jr, Ludwig EA, Savliwala M, Middleton E Jr, Slaughter RL. Lack of effect of atenolol on the pharmacokinetics of theophylline. Br J Clin Pharmacol 1988 Dec;26(6):800-2.
10.Corsi CM, Nafziger AN, Pieper JA, Bertino JS Jr. Lack of effect of atenolol and nadolol on the metabolism of theophylline. Br J Clin Pharmacol 1990 Feb;29(2):265-8.

Be the first to share your experience with this drug.

Review this Treatment

Find a Drug:

by name or medical condition or shape/color (Pill Identifier)

(for example: aspirin)

(for example: diabetes)

Report Problems to the Food and Drug Administration
 
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Health Solutions From Our Sponsors

Ask the pharmacist

Questions about medications? Get expert answers by video or live chat about allergies, pregnancy, sleep, and more.
See the Ask the Pharmacist event schedule.

Ask a Question

Popular Slideshows & Tools on WebMD

tea
What you should eat.
Woman sitting in front of UV lights
Is yours working?
woman using breath spray
What's causing yours?
colon xray
Get the facts.
MS Overview
Recognizing symptoms.
bowl of yogurt with heart shape
Eat for a healthy heart.
woman doing pushups
To help you get fit.
Colored x-ray of tooth decay
Know what to look for.
Woman sitting with child
Do you know the symptoms?
fruit drinks
Foods that can help you focus.
Sad dog and guacamole
Don't feed this to your dog.
Thyroid exam
See how much you know.

Women's Health Newsletter

Find out what women really need.

WebMD the app

Get trusted health information. Whenever. Wherever... with your iPhone, iPad or Android.

Find Out More

IMPORTANT: About This Section and Other User-Generated Content on WebMD

The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. Some of these opinions may contain information about treatment or uses of drug products that have not been approved by the U.S. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment.

Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately.