Skip to content
My WebMD Sign In, Sign Up

Azpan oral

Theophyllines/Hydantoins (mono deleted 03/26/2014)

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

When these two medicines are taken together, the effects of one or both medicines may decrease.

What might happen:

A decrease in the beneficial effects of one or both medicines may occur.

What you should do about this interaction:

If you experience difficulty breathing or your seizure control changes, contact your doctor. It may be necessary to adjust the dose of your medicines.Your healthcare professionals (e.g. doctor or pharmacist) may already be aware of this drug interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

References:

1.Taylor JW, Hendeles LWeinberger M, Lyon LW, Wyatt R, Riegelman S. The interaction of phenytoin and theophylline. Drug Intell Clin Pharm 1980; 14(9):638.
2.Marquis JF, Carruthers SG, Spence JD, Brownstone YS, Toogood JH. Phenytoin-theophylline interaction. N Engl J Med 1982 Nov 4; 307(19):1189-90.
3.Anonymous. Phenytoin-theophylline-quinidine interactions. N Engl J Med 1983 Mar 24;308(12):724-5.
4.Miller M, Cosgriff J, Kwong T, Morken DA. Influence of phenytoin on theophylline clearance. Clin Pharmacol Ther 1984 May;35(5):666-9.
5.Sklar SJ, Wagner JC. Enhanced theophylline clearance secondary to phenytoin therapy. Drug Intell Clin Pharm 1985 Jan;19(1):34-6.
6.Crowley JJ, Cusack BJ, Jue SG, Koup JR, Park BK, Vestal RE. Aging and drug interactions. II. Effect of phenytoin and smoking on the oxidation of theophylline and cortisol in healthy men. J Pharmacol Exp Ther 1988 May; 245(2):513-23.
7.Adebayo GI. Interaction between phenytoin and theophylline in healthy volunteers. Clin Exp Pharmacol Physiol 1988 Nov;15(11):883-7.
8.Landsberg K, Shalansky S. Interaction between phenytoin and theophylline. Can J Hosp Pharm 1988 Feb;41(1):31-2.
9.Nicholson JP, Basile SA, Cury JD. Massive theophylline dosing in a heavy smoker receiving both phenytoin and phenobarbital. Ann Pharmacother 1992 Mar;26(3):334-6.

Be the first to share your experience with this drug.

Review this Treatment

Find a Drug:

by name or medical condition or shape/color (Pill Identifier)

(for example: aspirin)

(for example: diabetes)

Report Problems to the Food and Drug Administration
 
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Ask the pharmacist

Questions about medications? Get expert answers by video or live chat about allergies, pregnancy, sleep, and more.
See the Ask the Pharmacist event schedule.

Ask a Question

Popular Slideshows & Tools on WebMD

hands on abdomen
Can you catch one?
Woman sitting in front of UV lights
Is yours working?
woman using breath spray
What's causing yours?
womans hand on abdomen
Are you ready for baby?
MS Overview
Recognizing symptoms.
bowl of yogurt with heart shape
Eat for a healthy heart.
woman doing pushups
To help you get fit.
Colored x-ray of tooth decay
Know what to look for.
Woman sitting with child
Do you know the symptoms?
mosquito
Stings, bites, burns, and more.
Allentown, PA
Are you living in one?
Thyroid exam
See how much you know.

Women's Health Newsletter

Find out what women really need.

WebMD the app

Get trusted health information. Whenever. Wherever... with your iPhone, iPad or Android.

Find Out More

IMPORTANT: About This Section and Other User-Generated Content on WebMD

The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. Some of these opinions may contain information about treatment or uses of drug products that have not been approved by the U.S. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment.

Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately.